Dehydrocholic Acid

A semisynthetic bile acid made from cholic acid. Dehydrocholic acid is used as a cholagogue, hydrocholeretic, diuretic, and as a diagnostic aid. The main use of dehydrocholic acid is as a digestive aid in the dietary supplement industry. It is typically formulated with enzymes like papain and pancreatin. Dehydrocholic acid increases the volume and the water content of the bile to improve biliary drainage. It is manufactured by oxidation of Cholic acid. Dehydrocholic acid is the most commonly employed of the bile acids for medicinal purposes.

Dehydrocholic acid is a Stimulant Laxative. It acts on the smooth muscles of the intestinal wall to cause a vigorous bowel movement. Dehydrocholic acid is an oxidation product of cholic acid (natural bile acid). Dehydrocholic acid exerts laxative and hydrocholeretic (increased volume and water content of bile) actions. The mechanisms of action are unknown. Unlike the natural bile acids and their conjugates, dehydrocholic acid does not readily form micelles (small aggregates of bile acids, fats and phosopholipids necessary for normal fat absorption) 28. Results usually occur within 6-12 hours. Dehydrocholic Acid & Docusate is a Combination Laxative and Stool Softener.

Packaging: 25kg fibre drums, sealed in a polyethylene liner.

Molecular Formula: C24H34O5
Molecular Weight: 402
CAS Number: 81-23-2