Deoxycholic acid is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilise fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
In nature, deoxycholic acid, which is referred to as a "secondary bile acid", is produced in the intestine from the salts of glycocholic and taurocholic acid (see cholic acid ) by the action of bacterial enzymes. Less than half of the deoxycholic acid is absorbed by the intestine and is returned the liver where it is conjugated and released into the gall bladder.
Deoxycholic acid is extracted from cattle bile, which is a by-product of the meat processing industry.
Historically deoxycholic acid was used as an intermediate for the production of corticosteroids, which have anti-inflammatory indications.
An emerging use of deoxycholic acid is as a biological detergent to lyse cells and solubilise cellular and membrane components
Packaging: Deoxycholic is sealed in a polyethylene liner and packed in 25kg fibre drums. Customer specific packaging can be provided.
Chemical name: Cholan-24-oic acid, 3,12-dihydroxy-, (3 alpha, 5 beta,12alpha)-
Molecular Formula: C24H40O4
Molecular Weight: 392
CAS Number: 83-44-3