Chrysin is the chemical name for a type of isoflavone molecule that has been demonstrated to be a potent aromatazation blocker. In other words, Chrysin minimizes the conversion of testosterone to either estrogen or DHT (dihyrdotestosterone). Chrysin is extracted from a fairly rare plant called the Passiflora Caerula. It is a natural extract yet more powerful than most anti-aromatase drugs you might be familiar with.
Chrysin belongs to the flavone class of flavonoids. Chrysin is found naturally in various plants including the Pelargonium species, which are germanium-like plants; the Passiflora or passion flower species, which include tropical passion fruit; and the Pinaceae species, including pine trees. Chrysin is a potent antioxidant that possesses vitamin-like effects in the body. It has been shown to induce an antiinflammatory effect, possibly through inhibition of the enzymes 5-lipoxygenase and cyclooxygenase inflammation pathways.
Chrysin (5, 7-dihydroxyflavone) belongs to a biologically active class known as bioflavonoids. Chrysin has been isolated from Passiflora plants, such as P. coerulea (used as a sedative in folklore medicine)1 and P. incarnate (maracuja "passion flower" which is well known in traditional medicine for its diverse biological effects). The effects of Chrysin include anti-inflammatory action, antiviral (including anti-HIV) action, vasodilatory effects and anxiety-reducing action. Chrysin has also been shown to have a potential role in drug metabolism and the chemoprevention of carcinogenesis. Laboratory studies, on in vitro and animal models, revealed that Chrysin inhibited the secretion of lysosomal enzymes and arachidonic acid, as well as the degranulation of mast cells, thereby reducing inflammation.
Chrysin's aromatase-inhibiting effects have made it popular among some body builders and athletes who use androgens. Very preliminary research suggests that chrysin may emerge as a useful anxiolytic agent, that it might aid in the control of morphine withdrawl and that it might have some chemopreventive properties in cardiovascular disease and cancer.
Chrysin happens is a very good inhibitor of aromatase, the enzyme in the body that converts testosterone into estradiol, and androstenedione into estrone. When this enzyme is inhibited, testosterone (as well as androstenedione) will tend to accumulate to higher concentrations. Indeed, numerous studies have shown that levels of testosterone rise when the action of the aromatase enzyme is blocked. It therefore comes as no surprise that chrysin is popular among athletes and other people eager to increase their testosterone levels, often in conjunction with supplemental testosterone precursors. Doses of 500-1000 mg three times per day are typically used.
Chemical Name: 5,7-Dihydroxyflavone
CAS NO.: 480-40-0
Characteristic: Off-white or pale yellow fine powder.
Assay(HPLC): 99.0% min.