Xenadrine provides a continuous supply of energy-promoting herbs and amino acids that support your body´s natural fat-burning capacity. Xenadrine represents the most sophisticated natural diet supplement in the world. It is research-proven, medically approved, extremely effective, and 100% natural. Xenadrine works by inducing thermogenesis, the 'speeding up' of the metabolism, and reducing the appetite, thus promoting weight-loss. The following provides a break-down on the action of individual Xenadrine ingredients.
Citrus aurantium in Xenadrine
Citrus aurantium is the botanical name for a fruit known as zhi shi in traditional Chinese medicine and as bitter orange or sour orange in other countries. The unripe fruit contains synephrine - a chemical that is structurally related to ephedrine - as well as octopamine and tyramine. Like ephedrine, synephrine has the ability to increase metabolic rate and lipolysis (fat breakdown). Synephrine is also a mild appetite suppressant and an energy enhancer. (The Chinese use it to stimulate the Qi, or energy force.) But unlike ephedrine, synephrine has much less impact on the central nervous system. This makes it easier to tolerate for people who are sensitive to ephedrine. The effects of synephrine are greatly increased when it is combined with caffeine.
Caffeine in Xenadrine
The caffeine sources in Xenadrine are green tea extract, cocoa extract and yerba mate. There is no difference in the caffeine of these three herbs - caffeine is caffeine. They do have some other differences, however.
Green Tea in Xenadrine
Green tea contains potent antioxidant compounds called polyphenols. There are four primary polyphenols in green tea. While all four appear to have protective value, epigallocatechin gallate (EGCG) occurs in the greatest amounts and has the strongest benefits. EGCG is an antioxidant that is several times more potent than vitamin E. It also prolongs the life of norepinephrine, which triggers thermogenesis. As a result, EGCG keeps the thermogenic process going for a longer period of time, allowing Xenadrine to boost your metabolic rate and facilitating fat loss.
Cocoa extract in Xenadrine
Cocoa extract comes from the plant Theobroma cacao. It contains a relatively small amount of caffeine along with larger amounts of theobromine, the primary metabolite of caffeine. Other plant chemicals in cocoa include PEA (phenylethylamine) and tyramine. PEA has been shown to increase attention span, while tyramine (a breakdown product of tyrosine) has a chemical structure that is similar to epinephrine and norepinephrine. Everyone who has eaten chocolate knows that cocoa can have a stimulating effect when consumed in sufficient quantities. (Unfortunately, it also has a lot of calories - hardly what you need while dieting.) The amount of cocoa extract in Xenadrine is not indicated.
Yerba mate in Xenadrine
Yerba mate (Ilex paraguariensis) is a tree that grows in Brazil, Argentina and Paraguay. The people of these countries have used it for centuries as a tonic and stimulant. The leaves of this plant contain caffeine as well as smaller amounts of theophylline and theobromine, two plant chemicals that also stimulate the central nervous system. Some reports indicate that yerba mate may have thermogenic properties in its own right, and this warrants its inclusion in the Xenadrine formulation.
As far as fat burning is concerned, the primary active ingredient in green tea extract and yerba mate is caffeine. This plant chemical is rapidly absorbed by the body and remains in circulation for more than seven hours. Plasma concentrations reach a peak one hour after it is consumed. It is then slowly metabolized, with a half-life of four to six hours.
Caffeine has been shown to dramatically increase free fatty-acid levels, providing the body with a fuel source that it can use instead of the glycogen stored in your liver and muscles. In fact, one Xenadrine study found a 100% increase in plasma free fatty acids after the subjects took 330 mg of caffeine.
At the same time, caffeine has been shown to increase adrenaline levels. This "fight-or-flight" hormone increases alertness and boosts energy levels, helping you to go through your daily tasks with less food intake. Most people experience a reduced appetite when their adrenaline levels are high, usually because they are focused on more essential tasks. With these two mechanisms, it's easy to understand why caffeine in Xenadrine is important for jump-starting your weight-loss efforts.
L-tyrosine in Xenadrine
L-tyrosine is the amino acid tyrosine in free (unbound) form, while acetyl-L-tyrosine is the same amino acid tied to an acetyl molecule. Both are bioavailable forms of tyrosine, an amino acid that plays an important role in human metabolism. It is the precursor to stimulatory neurotransmitters such as epinephrine, norepinephrine, dopamine and some of the thyroid hormones. All of these neurotransmitters and hormones play important roles in maintaining your metabolic rate. Logically, if you have a greater supply of these precursors, you can nudge your metabolism up a bit, helping you to shed unwanted pounds. Several studies have also shown that tyrosine increases the benefits of caffeine/ephedrine products, in part by curbing appetite. Tyrosine appears to reduce stress and fatigue as well, putting you in a better state of mind and making it easier to stick to your diet and exercise program. The amount of L-tyrosine in Xenadrine is not indicated on the product label.
Xenadrine Results From Ginger root
Ginger (Zingiber officinale) is indigenous to tropical Asia and is now cultivated in tropical areas throughout the world. The rhizome, which is technically an underground stem instead of a root, contains oleoresins that are rich in gingerols. These compounds have a variety of sedative effects. Ginger is traditionally used to calm the stomach and as a treatment for motion sickness. Since some individuals experience gastrointestinal upset with caffeine and other stimulatory chemicals, ginger should help to eliminate this occasional side effect. Ginger in Xenadrine does not have any fat-burning properties.
Di-methionine in Xenadrine
Methionine is an essential amino acid that assists in the breakdown of fats. For this reason, it is sometimes called a lipotropic. Methionine is a bioavailable source of methyl groups, which have a number of important roles in the body. This amino acid also contains sulfur, a mineral with antioxidant properties that is necessary for healthy skin, hair, tendons and ligaments. Methionine must be obtained from the diet, and is thus readily supplementable by Xenadrine. It is the precursor for the amino acids cystine and cysteine. Methionine is one of the three amino acids the body uses to make creatine, an important energy molecule.
DMAE in Xenadrine
DMAE (dimethylaminoethanol) is a precursor to choline in the body. This can boost the level of the neurotransmitter acetylcholine in the brain. Unlike many nutrients, DMAE is able to cross the blood-brain barrier. This gives it the potential to enhance attention span and alertness. DMAE supplementation through Xenadrine or another supplement has been shown to increase mental focus and energy levels, which ought to facilitate your adherence to your diet program.
Grape seed extract in Xenadrine
Grape seed extract contains a number of flavonoids and other compounds with significant antioxidant properties. It has been found to be a stronger neutralizer of free radicals than even vitamins C and E. Since exercise (which is needed to help create a caloric deficit) results in greater numbers of free radicals, taking an antioxidant such as grape seed extract has health benefits. Some makers of grape seed extract claim that their "unique" product also has the ability to redirect fatty acids away from the adipose tissues storage so they can be metabolized, resulting in less body fat over time. However, no published scientific study into Xenadrine or another weight-loss drug has shown this to be true.