Etodolac is a member of the non-steroidal anti-inflammatory drug (NSAIDs) family. As a group, NSAIDs are non-narcotic relievers of mild to moderate pain of many causes, including injury, menstrual cramps, arthritis, and other musculoskeletal conditions. Since the response to different NSAIDs varies from patient to patient, it is not unusual for a doctor to try different NSAIDs for any given condition.

Etodolac is a pyranocarboxylic acid, chemically designated as (±) 1,8-diethyl-1,3,4,9-tetrahydropyrano-[3,4-b]indole-1-acetic acid. Etodolac is a white crystalline compound, insoluble in water, but soluble in alcohols, chloroform, dimethyl sulfoxide, and aqueous polyethylene glycol.

Etodolac is used for the treatment of inflammation and pain caused by osteoarthritis and rheumatoid arthritis as well as soft tissue injuries, such as tendinitis and bursitis. It is also used for rapid relief of mild to moderate pain, such as with menstrual cramps. Etodolac reduces inflammation and pain by blocking production and release of chemicals that produce it.