Vitamin B6

Vitamin-type drugs are indispensable nutritious components in human body. Its main function is to take part in the metabolism of lipid and amino acid. Clinically it is commonly used in seborrheic dermatitis, seborrheic baldness, sideroblastic anemia, congestive heart failure, chronic infection and fever, isoniazid toxicosis, nausea and vomiting of pregnant women. With the stable elevation of material life level and the requirements for life quality of humankind, vitamin B6 has been widely applied to medicine, health-care product, food, cosmetic and feed.

Vitamin B6 is a water-soluble vitamin that exists in three major chemical forms: pyridoxine, pyridoxal, and pyridoxamine. It performs a wide variety of functions in your body and is essential for your good health. For example, vitamin B6 is needed for more than 100 enzymes involved in protein metabolism. It is also essential for red blood cell metabolism. The nervous and immune systems need vitamin B6 to function efficiently, and it is also needed for the conversion of tryptophan (an amino acid) to niacin (a vitamin).
Vitamin B6 is white or white-like crystal or crystal powder, which is inodorous, and tastes sour and bitter; it gradually deteriorates when exposed the sunlight.

This product is readily soluble in water and slightly soluble in ethanol, and non-soluble in chloroform and aether.
Smelting Point: The smelting point of this product is 205-209°C,and it decomposes when smelting.

(1)Take about 10mg of this product and add 100 ml of water to solve it. Put 1 ml of the solution into the test tube A and B with 2 ml 20% sodium acetate solution respectively, and put 1 ml water and 4% boric acid solution into test tubes A and test tube B respectively; evenly mix the solution and quickly add 1 ml chloro-imido-2,6-dichloro-chinone. The test tube A will appear blue and become red after a few minutes, and the blue color will not appear in test tube B.
(2)Add this product into hydrochloric acid solution (9-1000) to make 10µg/ml solution and assay it with spectrophotometer. There will be maximal absorption at the 291 nm wavelength with the absorptivity of about 0.43.
(3)The absorbing atlas of infrared ray of this product conforms to the controlling atlas.
(4)he identifying reaction for chloride in the water solution of this product.
[Test]Clarity of the solution: After solving 1.0 g of this product in 10 ml water, the solution should be clarified; if appearing turbid, compare it with No.1 turbidity standard solution and it should be thinner.
Acidity: Solve 1.0g of this product in 10 ml water and assay it. pH should be 2.4-3.0.
Weight Loss of Desiccation: Desiccate this product at 105 to constant weight. The weight loss should not be over 0.2% and the burned residue not over 0.1%.
Heavy Metal: Add 2.0 g of this product in 20ml water and after added with ammoniac solution it should appear neutral reaction in litmus paper test.
[Content Assay] Precisely measure this product with the error permission of 0.15 g and add 20ml ice acetic acid and 5 ml mercury acetate. Mildly melt it and cool it. Add 1 drop crystal purple indication liquid and titrate the solution with the titrating solution of perchloric acid until bluish green and correct the titrating result with blank test. One ml titrating solution of perchloric acid equal to 20.56mg C8H11NO3·HCl.
[Storage] Hermetically sealed and stored in dark place.
[Preparation] (1)Vitamin B6 tablet, (2)Vitamin B6 Injection

Chemical name: 6-methyl-5-hydroxy-3,4-pyridine-bis(methanol)-hydrochloride
Molecular formula: C8H11NO3·HCl
Molecular weight: 205.64

Vitamin B6 specifications

Product Properties

Standard Specifications



Melting point

205.0-209.0 degrees C

Acidity PH


Loss on drying

Max. 0.2%

Residue on ignition

Max. 0.1%

Sulfate ash

Max. 0.1%

Heavy metals

Max. 10PPM

Assay (C8H11NO3·HCL) Calculated on the dried basis


Clarity and color of solution


Chloride content


Related substances


Organic volatile impurities