China Greatvista Chemicals

Tinidazole

Tinidazole is a 5-nitroimidazole-derivative with selective antimicrobial activity against anaerobic bacteria and protozoa. Tinidazole is an anti-parasitic drug widely used throughout Europe and the Third World as treatment for a variety of amebic and parasitic infections. It is chemically similar to Flagyl — a drug with some unpleasant side effects that is used in the United States as first-line therapy for amebas. Tinidazole has similar side effects but you don't have take it as long. Tinidazole belongs to a group of antibiotics called the azoles. It works by entering the cell and binding to genetic material (DNA). This prevents the formation of further genetic material and therefore stops the bacteria from reproducing..

Tinidazole is an antibiotic used to treat infections caused by microorganisms that cause infections of the reproductive system and the gastrointestinal tract. The exact mechanism by which tinidazole works is not completely understood. However, tinidazole works to eliminate the microorganisms that can cause infections in your body.

The mode of action of tinidazole against anaerobic bacteria and protozoa involves penetration of the compound into the cell of the microorganism and subsequent damage of DNA strands or inhibition of their synthesis. Tinidazole is active against both protozoa and obligate anaerobic bacteria. The activity against protozoa involves Trichomonas vaginalis, Entamoeba histolytica and Giardia lamblia. Tinidazole is active against most anaerobic bacteria including Bacteroides fragilis, Bacteroides melaninogenicus, Bacteroides spp., Clostridium spp., Eubacterium spp., Fusobacterium spp., Gardnerella vaginalis, Peptococcus spp., Peptostreptococcus spp., and Veillonella spp.

Synonyms: simplotan, fasigyn
Molecular formula: C8H13N3O4S
CAS No: 19387-91-8