Lamivudine is used in combination with zidovudine to treat human immunodeficiency virus (HIV) infection in patients with acquired immunodeficiency syndrome (AIDS). It is also used alone or in combination with peginterferon to treat hepatitis B. Lamivudine is not a cure and may not decrease the number of HIV-related illnesses or hepatitis B cases. Lamivudine does not prevent the spread of HIV or hepatitis B to other people. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Lamivudine also is used in combination with zidovudine (Retrovir, AZT) to treat health-care workers or other individuals exposed to HIV infection after accidental contact with HIV-contaminated blood, tissues, or other body fluids.
Lamivudine is an oral medication that is used for the treatment of infections with the human immunodeficiency (HIV) and hepatitis B viruses. It is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and stavudine (Zerit). During infection with HIV, the HIV virus multiplies within the body's cells. The viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, HIV infection spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the virus' enzyme that forms this new DNA. Lamivudine first is converted within the body to its active form, lamivudine triphosphate. This active form is similar to a chemical, deoxycytidine triphosphate, that is used by reverse transcriptase to make new DNA. The reverse transcriptase uses lamivudine triphosphate instead of deoxycytidine triphosphate, and the lamivudine triphosphate interferes with the reverse transcriptase. Lamivudine does not kill existing HIV virus, and it is not a cure for HIV.
Lamivudine is a nucleoside reverse transcriptase inhibitor antiviral agent used in combination with other antivirals for the treatment of human immunodeficiency virus (HIV) infection. It works by slowing the growth of the virus. This medication is not a cure for HIV, nor does it prevent the passing of HIV to others. This medication contains lamivudine. The use of lamivudine, abacavir, and tenofovir in combination may not be effective in treating HIV infection.
Lamivudine stops HIV from replicating by blocking the reverse transcriptase enzyme. This enzyme is critical for translating the genetic information of the virus (RNA) into the genetic information of the cell (DNA). The virus cannot take over the cell's machinery without the function of the reverse transcriptase enzyme. Thus, lamivudine may help lower viral load and increase CD4 count. Lamivudine is proven to work well only when taken in combination with other anti-HIV medications.
There is no cure for HIV, but lamivudine is one of a number of medications that lowers the amount of virus in the body (viral load) and slows the progression of the disease from HIV to AIDS. Lamivudine is used in conjunction with other anti-HIV drugs that attack the HIV virus in different ways. This helps prevent the virus becoming resistant to the medicine.