Pantoprazole is in a class of drugs called proton pump inhibitors (PPI) which block the production of acid by the stomach. Other drugs in the same class include lansoprazole (Prevacid), omeprazole (Prilosec) and rabeprazole (Aciphex). Proton pump inhibitors are used for the treatment of conditions such as ulcers, gastroesophageal reflux disease (GERD) and Zollinger-Ellison Syndrome that are caused by stomach acid. Pantoprazole, like other proton-pump inhibitors, blocks the enzyme in the wall of the stomach that produces acid. By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal. Pantoprazole decreases the amount of acid produced in the stomach.
Pantoprazole is a proton pump inhibitor that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H+, K+)-ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect is dose-related and leads to the inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus. The binding to the (H+, K+)-ATPase results in a duration of antisecretory effect that persists longer than 24 hours.
Pantoprazole is used to treat damage to the esophagus associated with gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid production (e.g. Zollinger-Ellison Syndrome). Pantoprazole is used for the short-term treatment of erosive esophagitis, a severe form of gastroesophageal reflux disease (GERD) or heartburn. This medication decreases the amount of acid made in the stomach. It is sometimes prescribed to treat other conditions in which the stomach produces too much acid; ask your doctor or pharmacist for more information.